Research library

The studies behind the headlines, read from the papers themselves. Each entry says what the researchers found, what kind of study it was, how big it was, what it can't tell you, and who paid for it.

Studies in peopleAnimal studiesCell or tissue studiesMeasurements, sampling, models and reviews

  1. Review, landmark study

    The Lancet Countdown on health and plastics

    Landrigan PJ et al., The Lancet, 2025

    Launches an indicator-based global monitoring system for plastics and health. It states that plastics cause disease and death from infancy to old age, with health-related economic losses exceeding US$1.5 trillion a year, and that production grew from 2 Mt in 1950 to 475 Mt in 2022, projected to reach 1,200 Mt by 2060.

    Two Department of Error notices (September and October 2025) are linked to the paper; we have not read what they correct.

  2. Human study (observational), Autopsy liver, kidney and brain from about 20–28 decedents per timepoint (2016 and 2024), plus 12 brains with dementia, landmark study

    Bioaccumulation of microplastics in decedent human brains

    Nihart AJ et al., Nature Medicine, 2025

    Pyrolysis-GC/MS reported plastic, mostly polyethylene, in liver, kidney and brain. Median brain concentrations were 3,345 µg/g (2016) and 4,917 µg/g (2024), far above liver (433) and kidney (404) in 2024; concentrations rose between 2016 and 2024. Brains from 12 people with dementia had even higher levels.

    Author correction (31 March 2025) fixed duplicated supplementary images and incorrect scale bars; authors say spectra data were unaffected. Monikh et al. (Nature Medicine, Nov 2025) argued limited contamination controls and lack of validation may affect the reported concentrations; the authors replied acknowledging uncertainties, including possible lipid interference.

  3. Human study (observational), 304 patients enrolled, 257 followed for a mean 33.7 months, landmark study

    Microplastics and nanoplastics in atheromas and cardiovascular events

    Marfella R et al., New England Journal of Medicine, 2024

    Polyethylene was detected in carotid artery plaque from 150 of 257 patients (58.4%) having surgery, and PVC in 31 (12.1%). Over about 34 months, patients with plastic in their plaque had a higher risk of heart attack, stroke or death from any cause (hazard ratio 4.53; 95% CI 2.00–10.27).

    Pyrolysis-GC/MS measurement of polyethylene and PVC in fatty biological tissue has been challenged (Rauert et al. 2025; Monikh et al. 2025), which applies to plaque as well. NEJM published reader correspondence on the study (May 2024, doi 10.1056/NEJMc2404154).

  4. Lab measurement, 3 brands of bottled water bought at one large US retailer, landmark study

    Rapid single-particle chemical imaging of nanoplastics by SRS microscopy

    Qian N et al., Proceedings of the National Academy of Sciences, 2024

    Using a new stimulated Raman scattering imaging method that can identify single plastic particles under 100 nm, the team estimated about 2.4 ± 1.3 × 10^5 plastic particles per litre of bottled water, about 90% of them nanoplastics. That is orders of magnitude more than earlier counts that could only see microplastics. Polyamide was a common major contributor across the three brands.

    Materić (PNAS 2024, doi 10.1073/pnas.2411099121) argued the blanks were inappropriate because the paper's own SI says the lab's ultrapure water had similar plastic contamination to the bottled water. The authors replied (doi 10.1073/pnas.2415874121) that contaminated lab water would have been the wrong blank and that brand profiles differed.

  5. Lab measurement, Polypropylene baby-food containers and a polyethylene reusable food pouch, landmark study

    Assessing the release of microplastics and nanoplastics from plastic containers and reusable food pouches: implications for human health

    Hussain KA et al., Environmental Science & Technology, 2023

    Microwaving released the most particles: some containers shed up to 4.22 million microplastics and 2.11 billion nanoplastics per square centimetre in 3 minutes. Six months in the fridge or at room temperature also released millions to billions. Modelled intake peaked at 20.3 ng/kg per day for infants drinking microwaved water and 22.1 for toddlers eating microwaved dairy. At 1,000 µg/mL, extracted particles killed about 77% of human kidney cells in a dish.

  6. Review, landmark study

    The Minderoo-Monaco Commission on Plastics and Human Health

    Landrigan PJ et al., Annals of Global Health, 2023

    A large commission review of plastics' harms across their life cycle, from extraction and production to disposal, covering human health, the ocean, economic costs and vulnerable groups, with recommendations for a global plastics treaty.

    Correction (Annals of Global Health, 2023, doi 10.5334/aogh.4331): its figure of 90,762 DEHP-attributable US deaths a year among 55–64-year-olds, and the linked US$490 billion cost, was the sum of two years (2013 and 2014), not one year.

  7. Human study (observational), 22 healthy adult blood donors, landmark study

    Discovery and quantification of plastic particle pollution in human blood

    Leslie HA et al., Environment International, 2022

    The first study to measure plastic particles (700 nm and larger) in human whole blood by pyrolysis-GC/MS. Plastic was quantifiable in 17 of 22 donors (77%), with a mean of 1.6 µg/ml; PET, polyethylene and styrene polymers were most common, and polypropylene was below the limit of quantification.

    Rauert et al. 2025 (Environmental Science & Technology) concluded Py-GC/MS is currently unsuitable for polyethylene and PVC in biological matrices because of interferences, which bears on blood-plastic mass figures generally. A letter to the editor (Kuhlman, Environment International 2022, doi 10.1016/j.envint.2022.107400) also commented on the paper; we have not read it.

  8. Review, landmark study

    Dietary and inhalation exposure to nano- and microplastic particles and potential implications for human health

    World Health Organization et al., WHO report (ISBN 9789240054608), 2022

    WHO reviewed studies up to December 2021 on micro- and nanoplastics in food, drinking water and air. It found the available data were of only very limited use for assessing risk, because toxicity studies used doses and particle types that do not match real exposure, so no quantitative risk assessment was possible.

  9. Human study (observational), 6 placentas, landmark study

    Plasticenta: First evidence of microplastics in human placenta

    Ragusa A et al., Environment International, 2021

    Raman microspectroscopy found 12 pigmented microplastic fragments (5–10 µm) in 4 of 6 placentas, on the maternal side, fetal side and membranes. Three were identified as polypropylene; for the other nine only the pigment could be identified.

  10. Lab measurement, 10 polypropylene infant feeding bottle products; exposure modelled for 48 regions, landmark study

    Microplastic release from the degradation of polypropylene feeding bottles during infant formula preparation

    Li D et al., Nature Food, 2020

    Polypropylene baby bottles released up to 16.2 million microplastic particles per litre during formula preparation. Sterilising and using hot water significantly increased release. Modelled exposure for infants up to 12 months ranged from 14,600 to 4,550,000 particles per day depending on region.

  11. Modelling, 402 data points from 26 studies (over 3,600 processed samples), landmark study

    Human consumption of microplastics

    Cox KD et al., Environmental Science & Technology, 2019

    Combining published measurements with the American diet, the authors estimate 39,000 to 52,000 microplastic particles eaten per year depending on age and sex, rising to 74,000 to 121,000 when inhalation is added. Meeting water needs only from bottled water could add about 90,000 particles a year, versus about 4,000 for tap water only.

    A correction was published (Environmental Science & Technology 2020, doi 10.1021/acs.est.0c04032). We have not been able to read what it changes, so check it before quoting these figures.

  12. Review, landmark study

    Are we speaking the same language? Recommendations for a definition and categorization framework for plastic debris

    Hartmann NB et al., Environmental Science & Technology, 2019

    Researchers used inconsistent size classes and definitions for microplastics. This paper proposes a common framework: plastic debris is defined by polymer composition, solid state and insolubility, then categorised by size, shape, colour and origin, to make studies comparable.

  13. Lab measurement, Commercial nylon and PET 'silken' teabags, landmark study

    Plastic teabags release billions of microparticles and nanoparticles into tea

    Hernandez LM et al., Environmental Science & Technology, 2019

    Steeping one plastic teabag at 95 °C released about 11.6 billion microplastics and 3.1 billion nanoplastics into a cup, matched to the bag's nylon and PET by FTIR and XPS. The authors say this is several orders of magnitude above plastic loads reported in other foods. Water fleas exposed to the released particles showed dose-dependent behavioural and developmental effects.

    Busse et al. (Environmental Science & Technology 2020, doi 10.1021/acs.est.0c03182) published a comment questioning the particle counts; as summarised by Cella et al. 2022 (EU JRC), they concluded the material was partly soluble oligomers. The authors replied (doi 10.1021/acs.est.0c06422) that Busse et al. also found plastic teabags release particles but used different methods, so the numbers cannot be compared. We have not read the comment itself.

  14. Review, 50 studies of freshwater, groundwater, tap and bottled water, landmark study

    Microplastics in freshwaters and drinking water: critical review and assessment of data quality

    Koelmans AA et al., Water Research, 2019

    Scoring 50 studies of microplastics in freshwater and drinking water against quality criteria, the authors found only 4 met all of them. Reported concentrations spanned ten orders of magnitude (0.01 to 10^8 particles per cubic metre). Polyethylene and polypropylene were most common, then polystyrene, PVC and PET. They propose best practice for sampling, blanks and identification.

  15. Human study (observational), 8 healthy volunteers, one stool sample each, landmark study

    Detection of various microplastics in human stool: a prospective case series

    Schwabl P et al., Annals of Internal Medicine, 2019

    All 8 stool samples from volunteers in Europe and Asia contained microplastics, a median of 20 particles (50–500 µm) per 10 g of stool. Nine plastic types were found; polypropylene and PET were most abundant.

  16. Review, landmark study

    Microplastics in drinking-water

    World Health Organization et al., WHO report (ISBN 9789241516198), 2019

    WHO's first review concluded there was no reliable information suggesting an overt health concern from microplastics in drinking water at current levels, while stressing this does not mean they are harmless. Particles over 150 µm are likely excreted, and uptake of smaller ones is expected to be limited (around 0.3% or less).

    Superseded in scope by WHO's 2022 report on dietary and inhalation exposure, which reached a similar 'insufficient data' conclusion.

  17. Lab measurement, 259 bottles of 11 brands bought in 9 countries, landmark study

    Synthetic polymer contamination in bottled water

    Mason SA et al., Frontiers in Chemistry, 2018

    93% of 259 bottles showed some microplastic contamination. After blank correction there were on average 10.4 particles per litre larger than 100 µm, and about 325 per litre when Nile Red-stained particles down to 6.5 µm were counted. Polypropylene, the usual cap plastic, made up 54% of confirmed polymers, pointing partly at packaging and bottling.

  18. Environmental sampling, 2 apartments and 1 office (Paris area), 1 outdoor site, landmark study

    A first overview of textile fibers, including microplastics, in indoor and outdoor environments

    Dris R et al., Environmental Pollution, 2017

    The first study of fibres in indoor and outdoor air found 1.0–60.0 fibres per cubic metre indoors versus 0.3–1.5 outdoors. Fibres settled indoors at 1,586–11,130 per square metre per day, building up to 190–670 fibres per mg of vacuum dust. 67% were natural (mostly cellulose) and 33% contained petrochemicals, mainly polypropylene.

  19. Review, landmark study

    Plastic and human health: a micro issue?

    Wright SL et al., Environmental Science & Technology, 2017

    An early, widely cited review of how microplastics might harm people: through particle toxicity and immune responses if inhaled or ingested, leaching of additives and monomers, and microbes carried on particles. It concluded health effects were unknown and exposure data were the key gap.

  20. Lab measurement, Polyester, polyester-cotton and acrylic fabrics washed under different conditions, landmark study

    Release of synthetic microplastic plastic fibres from domestic washing machines: effects of fabric type and washing conditions

    Napper IE et al., Marine Pollution Bulletin, 2016

    Polyester-cotton blend shed significantly fewer fibres than polyester or acrylic, with effects of temperature, detergent and conditioner interacting in complex ways. The authors estimate an average 6 kg wash of acrylic could release over 700,000 fibres.

  21. Human study (observational), 1,455 US adults (NHANES 2003–2004), landmark study

    Association of urinary bisphenol A concentration with medical disorders and laboratory abnormalities in adults

    Lang IA et al., JAMA, 2008

    An early large human study of BPA and adult disease: higher urinary BPA was associated with cardiovascular diagnoses (odds ratio 1.39 per standard deviation) and diabetes (odds ratio 1.39), plus abnormal liver enzymes.

    JAMA ran an accompanying editorial (vom Saal and Myers, 2008) and three letters in 2009 commenting on the analysis (e.g., Young and Yu, doi 10.1001/jama.2009.122), with an author reply. We have not read them.

  22. Human study (observational), 85 mother-son pairs with prenatal urine samples (134 boys examined), landmark study

    Decrease in anogenital distance among male infants with prenatal phthalate exposure

    Swan SH et al., Environmental Health Perspectives, 2005

    Boys whose mothers had higher levels of four phthalate metabolites in pregnancy had a shorter anogenital index (anogenital distance relative to weight), a marker of reduced male hormone action before birth seen in phthalate-exposed rodents. For the top versus bottom quarter of MBP, the odds of a shorter-than-expected index were 10.2 times higher (95% CI 2.5–42.2).

    An erratum was published (EHP, September 2005; content not checked). Employees of cosmetics trade associations (McEwen and Renner, EHP 2006) questioned the validity of the measure; Swan replied.

  23. Lab measurement, Water, soft drinks, beer and wine sold in France, in plastic, glass, carton, can and bag-in-box

    Microplastic contaminations in a set of beverages sold in France

    Chaïb I et al., Journal of Food Composition and Analysis, 2025

    Mean levels were 2.9 microplastics per litre in water, 31.4 in colas, 28.5 in teas, 45.2 in lemonades, 82.9 in beers and 8.2 in wines. Drinks in glass bottles were the most contaminated. Most particles matched the colour and outer paint of the metal caps, which the authors suspect are the main source.

  24. Animal study, Male C57BL/6J mice (small groups imaged)

    Microplastics in the bloodstream can induce cerebral thrombosis by causing cell obstruction and lead to neurobehavioral abnormalities

    Huang H et al., Science Advances, 2025

    Live brain imaging in mice showed that 5 µm fluorescent polystyrene microspheres, given by gavage or injected into the blood, were engulfed by immune cells that then lodged in brain capillaries, forming blockages that reduced blood flow and were linked to movement and behaviour changes.

  25. Review, Narrative review plus a survey of 1,135 German speakers

    Microplastics: state of the evidence on health effects and public perception

    Janzik R et al., Deutsches Ärzteblatt International, 2025

    A review by scientists at Germany's Federal Institute for Risk Assessment (BfR) for doctors. Most ingested or inhaled microplastic is excreted; about 0.3% of 1–10 µm particles are absorbed in the gut. Particles have been found in organs such as placenta and plaque, but no causal link to health effects has been proven. In their survey, 84% believed microplastics can worsen existing illness.

    A 2026 letter to the editor (Saha et al., doi 10.3238/arztebl.m2025.0244) argued the review is incomplete: it leaves out plastics' chemical and environmental harms and conveys apparent safety. The authors replied (doi 10.3238/arztebl.m2025.0245).

  26. Review

    Challenges in studying microplastics in human brain

    A Monikh F et al., Nature Medicine (Matters Arising), 2025

    A published critique of Nihart et al. 2025 (the brain-plastic study). The authors argue that the study appears to face methodological challenges, such as limited contamination controls and lack of validation steps, which may affect the reliability of the reported brain concentrations.

  27. Lab measurement, Method validation plus a pilot of Australian blood samples

    Assessing the efficacy of pyrolysis-gas chromatography-mass spectrometry for nanoplastic and microplastic analysis in human blood

    Rauert C et al., Environmental Science & Technology, 2025

    Tested whether pyrolysis-GC/MS can reliably measure plastic in human blood. Blood produced false polyethylene and PVC signals; a new extraction reduced but did not remove the polyethylene interference, realistic detection limits were up to 20 times higher than in clean water, and in the pilot no other polymer exceeded detection limits. The authors conclude the method is currently not suitable for PE and PVC in biological samples.

  28. Human study (observational), 15 autopsied adults in São Paulo

    Microplastics in the olfactory bulb of the human brain

    Amato-Lourenço LF et al., JAMA Network Open, 2024

    Micro-FTIR found 16 synthetic polymer particles and fibres in the olfactory bulbs (the brain's smell centre, just above the nose) of 8 of 15 deceased adults. Polypropylene was most common (43.8%); particles measured 5.5–26.4 µm. The authors suggest the nose could be a route into the brain.

  29. Human study (observational), 62 placentas

    Quantitation and identification of microplastics accumulation in human placental specimens using pyrolysis gas chromatography mass spectrometry

    Garcia MA et al., Toxicological Sciences, 2024

    Pyrolysis-GC/MS reported microplastics in all 62 placentas, from 6.5 to 685 µg per gram of tissue (mean 126.8 µg/g). Polyethylene made up 54% of the plastic mass; PVC and nylon about 10% each.

  30. Human study (observational), 23 human and 47 dog testes

    Microplastic presence in dog and human testis and its potential association with sperm count and weights of testis and epididymis

    Hu CJ et al., Toxicological Sciences, 2024

    Pyrolysis-GC/MS found microplastics in all 23 human and 47 dog testes, with mean totals of 328.44 µg/g in humans and 122.63 µg/g in dogs; polyethylene dominated. In dogs, PVC and PET were negatively correlated with testis weight, and polycarbonate and ABS with lower sperm count.

  31. Lab measurement, 203 black plastic household products bought in the US

    From e-waste to living space: flame retardants contaminating household items add to concern about plastic recycling

    Liu M et al., Chemosphere, 2024

    Of 203 black plastic household products screened, those with more than 50 ppm bromine were analysed, and flame retardants were found in 85% of them at up to 22,800 mg/kg, including the restricted deca-BDE. Styrene-based plastics typical of electronics had much higher levels. The original abstract estimated median BDE-209 intake of 34,700 ng/day from contaminated utensils; a correction lowered this to 7,900 ng/day.

    Two corrigenda: Chemosphere 2025 (vol. 370; doi 10.1016/j.chemosphere.2024.143903) fixed the reference dose for a 60 kg adult from 42,000 to 420,000 ng/day, so intake is an order of magnitude below it, not 'approaching' it; Chemosphere 2025 (doi 10.1016/j.chemosphere.2025.144552) corrected a misapplied formula, lowering 34,700 to 7,900 ng/day. Authors say core conclusions stand.

  32. Human study (observational), 59 postpartum women in Thailand

    Detection of microplastics in human breast milk and its association with changes in human milk bacterial microbiota

    Saraluck A et al., Journal of Clinical Medicine, 2024

    Raman spectroscopy found microplastics in 23 of 59 breast milk samples (38.98%), mainly polypropylene, polyethylene, polystyrene and PVC. Milk with detectable plastic had a different bacterial makeup (more Staphylococcus and Streptococcus).

  33. Modelling

    Chemicals used in plastic materials: an estimate of the attributable disease burden and costs in the United States

    Trasande L et al., Journal of the Endocrine Society, 2024

    Estimated US$249 billion (range $226–289 billion) in US disease costs in 2018 from chemicals used in plastics: PBDE flame retardants, phthalates, bisphenols and PFAS. Most came from PBDEs; phthalates accounted for $66.7 billion and PFAS $22.4 billion. The authors estimated that plastics account for 97.5% of BPA exposure and 98% of DEHP exposure.

    A correction (February 2024) added missing repository details for the supplementary material (reference 11); the estimates were not changed.

  34. Lab measurement

    Drinking boiled tap water reduces human intake of nanoplastics and microplastics

    Yu Z et al., Environmental Science & Technology Letters, 2024

    Boiling tap water made polystyrene, polyethylene and polypropylene particles co-precipitate with calcium carbonate scale. In hard water (over 120 mg/L CaCO3), boiling removed at least 80% of particles between 0.1 and 150 µm. The authors suggest boiling, then removing the scale, as a simple household step.

  35. Lab measurement, 28 recycled HDPE pellet samples from 13 countries, plus 1 virgin HDPE reference

    A dataset of organic pollutants identified and quantified in recycled polyethylene pellets

    Carmona E et al., Data in Brief, 2023

    Chemical screening of 28 recycled polyethylene pellet samples, mostly from the Global South, detected and quantified 491 organic compounds and tentatively identified 170 more, including pesticides, pharmaceuticals, industrial chemicals and plastic additives. The processing aid N-ethyl-o-toluenesulfonamide was common at high concentrations.

  36. Human study (observational), 18 mother-infant pairs

    Detection of various microplastics in placentas, meconium, infant feces, breastmilk and infant formula: a pilot prospective study

    Liu S et al., Science of the Total Environment, 2023

    Laser infrared imaging found 16 types of microplastics across placentas, meconium (a newborn's first stool), infant stool at 6 months, breast milk and formula; polyamide and polyurethane dominated and over 74% were 20–50 µm. Questionnaires pointed to water, scrubs/toothpaste, feeding bottles and plastic toys as possible sources.

  37. Human study (observational), 10 semen samples from men in a polluted area of Campania, Italy

    Raman microspectroscopy evidence of microplastics in human semen

    Montano L et al., Science of the Total Environment, 2023

    Raman microspectroscopy found 16 pigmented microplastic fragments (2–6 µm) in 6 of 10 semen samples. Polymers included polypropylene, polyethylene, PET, polystyrene, PVC, polycarbonate, POM and acrylic.

  38. Modelling

    Estimating mouthing exposure to chemicals in children's products

    Aurisano N et al., Journal of Exposure Science & Environmental Epidemiology, 2022

    The authors built a model to predict how chemicals migrate from children's products into saliva during mouthing. Predictions matched lab data well (R² = 0.85). Migration ranged from 8 × 10^-7 to 32.7 µg per 10 cm² per minute, highest for plasticisers in PVC, and mouthing doses ranged from a median of 0.005 to 253 µg/kg body weight per day across chemicals and materials.

  39. Human study (observational), 6 patients with cirrhosis, 5 without liver disease (17 tissue samples)

    Microplastics detected in cirrhotic liver tissue

    Horvatits T et al., eBioMedicine, 2022

    Using Nile red staining and Raman spectroscopy, microplastics of 4–30 µm (six polymer types) were found in liver tissue from all six people with cirrhosis, while liver, kidney and spleen from people without liver disease tested negative.

  40. Human study (observational), 13 lung tissue samples from surgical patients

    Detection of microplastics in human lung tissue using μFTIR spectroscopy

    Jenner LC et al., Science of the Total Environment, 2022

    39 microplastics were found in 11 of 13 lung samples from living surgical patients: 1.42 per gram of tissue, or 0.69 per gram after subtracting background contamination. Polypropylene (23%) and PET (18%) were most common, and levels were highest in the lower lung.

  41. Lab measurement, Several scratched non-stick (PTFE-coated) pots

    Raman imaging for the identification of Teflon microplastics and nanoplastics released from non-stick cookware

    Luo Y et al., Science of the Total Environment, 2022

    The team developed Raman imaging algorithms to pick out weak PTFE (Teflon) signals on scratched non-stick surfaces. Combined with electron microscopy, they estimate that thousands to millions of Teflon micro- and nanoplastics might be released during a simulated cooking process.

  42. Human study (observational), 6 volunteers in southern Italy

    First evidence of microplastics in human urine, a preliminary study of intake in the human body

    Pironti C et al., Toxics, 2022

    Raman microspectroscopy found four pigmented microplastic fragments (4–15 µm) in urine from four of six volunteers, identified as polyethylene vinyl acetate, PVC, polypropylene and polyethylene.

  43. Human study (observational), 34 breastfeeding women

    Raman microspectroscopy detection and characterisation of microplastics in human breastmilk

    Ragusa A et al., Polymers, 2022

    Microplastics were found in 26 of 34 breast milk samples by Raman microspectroscopy, mostly polyethylene, PVC and polypropylene, sized 2–12 µm. No relationship was found with the mothers' diet, seafood or use of personal care products.

  44. Lab measurement, Silicone-rubber baby teats subjected to steam disinfection

    Steam disinfection releases micro(nano)plastics from silicone-rubber baby teats as examined by optical photothermal infrared microspectroscopy

    Su Y et al., Nature Nanotechnology, 2022

    Steam disinfection etched silicone teat surfaces and released flake- and oil-film-shaped particles of 0.6–332 µm, including polysiloxanes and imide-containing particles from the silicone and a polyamide resin additive. The authors estimate a baby could ingest more than 0.66 million such particles by age one, and global release from teat disinfection could reach 5.2 × 10^13 particles a year.

    Author correction (Nature Nanotechnology, published 31 May 2022): 'polyimides' in the abstract and text should read 'imides'.

  45. Human study (observational), 5,303 US adults (NHANES 2001–2010) followed to 2015

    Phthalates and attributable mortality: a population-based longitudinal cohort study and cost analysis

    Trasande L et al., Environmental Pollution, 2022

    Higher urinary levels of high-molecular-weight phthalates, especially DEHP metabolites, were linked to higher all-cause death (hazard ratio 1.14 for continuous levels; 1.48 in the top third) and to cardiovascular death. The authors extrapolated 90,761–107,283 attributable deaths among 55–64-year-old Americans and US$39.9–47.1 billion in lost productivity.

    The Minderoo-Monaco Commission's 2023 correction says that, on re-examination, this paper's death figure (which the Commission had cited as annual) appears to be based on 2013 and 2014 US population data combined, so it covers two years. The abstract states no period for the death figure itself; its objectives refer to attributable mortality in 2013-4.

  46. Lab measurement, Food-grade nylon bags and LDPE-lined hot beverage cups

    Common single-use consumer plastic products release trillions of sub-100 nm nanoparticles per liter into water during normal use

    Zangmeister CD et al., Environmental Science & Technology, 2022

    Food-grade nylon bags and paper cups lined with low-density polyethylene released more than 10^12 nanoparticles per litre into water, with mean diameters of 30–80 nm. The number released depended on water temperature, and in hot water nylon released 7 times more than the cups. The authors calculate one 300 mL hot cup releases roughly one particle for every seven cells in the body.

  47. Human study (observational), 20 autopsy lung samples

    Presence of airborne microplastics in human lung tissue

    Amato-Lourenço LF et al., Journal of Hazardous Materials, 2021

    Polymer particles (33) and fibres (4) were found in 13 of 20 lung tissue samples from autopsies in São Paulo. All particles were smaller than 5.5 µm and fibres were 8.12–16.8 µm; polyethylene and polypropylene were most frequent.

  48. Review

    Sampling and quality assurance and quality control: a guide for scientists investigating the occurrence of microplastics across matrices

    Brander SM et al., Applied Spectroscopy, 2020

    Because microplastics are everywhere, including in lab air, water and equipment, background contamination is a constant risk. This guide sets out quality assurance and control steps (blanks, clean handling, sampling design) for water, sediment, tissue and air samples so results are reproducible across labs.

  49. Lab measurement, Polyester garments with different fabric structures and yarns

    Microfiber release to water, via laundering, and to air, via everyday use: a comparison between polyester clothing with differing textile parameters

    De Falco F et al., Environmental Science & Technology, 2020

    Polyester garments released microfibres straight into the air during wear, and scaled up per person per year this was of a similar order to what laundering sends to wastewater. Tightly woven fabrics with highly twisted continuous-filament yarns shed least to both air and water; looser knits with short staple fibres shed most.

  50. Animal study, Pregnant Sprague Dawley rats, plus isolated placenta perfusion

    Nanopolystyrene translocation and fetal deposition after acute lung exposure during late-stage pregnancy

    Fournier SB et al., Particle and Fibre Toxicology, 2020

    Pregnant rats had 20 nm fluorescent polystyrene beads placed in their lungs late in pregnancy. Within 24 hours the particles were found in the placenta and fetal tissues, and fetal and placental weights were 7% and 8% lower than controls.

  51. Lab measurement, 73 homes in North Carolina (61 central, 12 southeastern), 16 PFAS

    Assessing the effectiveness of point-of-use residential drinking water filters for perfluoroalkyl substances (PFASs)

    Herkert NJ et al., Environmental Science & Technology Letters, 2020

    In 73 North Carolina homes, every under-sink dual-stage and reverse osmosis filter tested removed nearly all of 16 PFAS. Other activated-carbon filters (pitcher, faucet, fridge, countertop, single-stage under-sink) were variable, removing about 60–70% of long-chain PFAS but only about 40% of short-chain ones. In four of eight whole-house carbon systems, PFAS levels were higher after the filter.

  52. Environmental sampling, 286 indoor dust samples from 12 countries

    Microplastics in house dust from 12 countries and associated human exposure

    Zhang J et al., Environment International, 2020

    PET microplastics were found in every one of 286 dust samples at 38–120,000 µg/g (median 5,900 µg/g); polycarbonate at under 0.11–1,700 µg/g (median 8.8). Estimated median intake of PET from dust for infants ranged from 4,000 to 150,000 ng per kg body weight per day across countries.

  53. Human study (observational), 178 middle-aged women (about half African American); flosses tested for fluorine

    Serum concentrations of PFASs and exposure-related behaviors in African American and non-Hispanic white women

    Boronow KE et al., Journal of Exposure Science & Environmental Epidemiology, 2019

    Flossing with Oral-B Glide was associated with higher levels of some PFAS in blood, as were stain-resistant carpet or furniture and living in a city with PFAS-contaminated water. In African American women only, frequent eating of food from coated cardboard containers was linked to higher levels of four PFAS. Testing confirmed fluorine in Glide and competitor flosses.

  54. Environmental sampling, 3 apartments (Denmark)

    Simulating human exposure to indoor airborne microplastics using a Breathing Thermal Manikin

    Vianello A et al., Scientific Reports, 2019

    A breathing manikin in three apartments sampled 1.7–16.2 microplastic particles per cubic metre of air, analysed by FTIR imaging down to 11 µm. Synthetic particles were about 4% of identified particles (protein 91%, cellulose 4%). Polyester dominated (81%), then polyethylene (5%) and nylon (3%), and microplastics tended to be smaller than natural particles.

  55. Lab measurement, Single-use PET mineral water bottles with HDPE caps from several brands

    Does mechanical stress cause microplastic release from plastic water bottles?

    Winkler A et al., Water Research, 2019

    Opening and closing PET bottles 1, 10 and 100 times sharply increased plastic particles on the neck and especially the HDPE cap surfaces, with large differences between brands. Squeezing the bottles did not significantly raise particle counts in the water, and no stress cracks were found inside. The authors conclude the cap-and-neck system, not the bottle wall, is the main source with repeated reuse.

  56. Lab measurement, 159 tap water samples from around the world, 12 beer brands, 12 sea salt brands

    Anthropogenic contamination of tap water, beer, and sea salt

    Kosuth M et al., PLOS ONE, 2018

    81% of 159 tap water samples contained human-made particles, 98.3% of them fibres 0.1–5 mm long, at a mean of 5.45 particles per litre (range 0–61). Particles turned up in every beer and salt brand. The authors estimate an average person ingests over 5,800 synthetic particles a year from these three sources, 88% of it from tap water.

  57. Lab measurement, 96 plastic kitchen utensils (UK)

    Brominated flame retardants in black plastic kitchen utensils: concentrations and human exposure implications

    Kuang J et al., Science of the Total Environment, 2018

    Bromine was detected in 31 of 69 utensils bought before 2011 but only 3 of 27 bought after 2011, suggesting contamination from recycled electronics plastic. In simulated cooking, about 20% of flame retardants on average moved from utensils into hot oil. Estimated median exposure from cooking with contaminated utensils was 60 ng per day of total brominated flame retardants; skin contact was minimal.

  58. Lab measurement, About 200 second-hand plastic toys from the UK

    Concentrations and migratabilities of hazardous elements in second-hand children's plastic toys

    Turner A et al., Environmental Science & Technology, 2018

    XRF screening of about 200 second-hand toys found bromine, cadmium and lead frequently, at maximums of about 16,000, 20,000 and 5,000 µg/g. In simulated stomach acid tests on 26 toys, eight exceeded EU Toy Safety Directive migration limits for cadmium or lead, with yellow and red Lego bricks exceeding the cadmium limit tenfold.

  59. Lab measurement, Several facial scrub products

    Characterisation, quantity and sorptive properties of microplastics extracted from cosmetics

    Napper IE et al., Marine Pollution Bulletin, 2015

    Polyethylene microbeads extracted from facial scrubs had mean diameters of 164–327 µm, and between 4,594 and 94,500 beads could be released in a single use. In seawater the beads picked up phenanthrene and DDT much like other polyethylene particles, so they could carry pollutants.

  60. Lab measurement, 4 brands of nonstick frying pans; 3 brands of microwave popcorn

    Quantitation of gas-phase perfluoroalkyl surfactants and fluorotelomer alcohols released from nonstick cookware and microwave popcorn bags

    Sinclair E et al., Environmental Science & Technology, 2007

    Heated to normal cooking temperatures (179–233 °C surface), nonstick pans from four brands released 7–337 ng of PFOA per pan into the air. PFOA was still above 5 ng on the fourth use for both brands tested repeatedly. Microwave popcorn bags released 5–34 ng PFOA in their vapours; plain kernels in a polypropylene container released none detectable.