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Chemicals used in plastic materials: an estimate of the attributable disease burden and costs in the United States

Trasande L, Krithivasan R, Park K, Obsekov V, Belliveau M (2024). Journal of the Endocrine Society.

What they found

Estimated US$249 billion (range $226–289 billion) in US disease costs in 2018 from chemicals used in plastics: PBDE flame retardants, phthalates, bisphenols and PFAS. Most came from PBDEs; phthalates accounted for $66.7 billion and PFAS $22.4 billion. The authors estimated that plastics account for 97.5% of BPA exposure and 98% of DEHP exposure.

Read this too

A correction (February 2024) added missing repository details for the supplementary material (reference 11); the estimates were not changed.

What it can't tell you
A model that stacks disease-burden estimates from earlier studies, each assuming causal links; uncertain links (and the PFAS share, 16–96%) drive the totals. Not new health data.
Funding
US National Institutes of Health (P2C ES033423) and The Passport Foundation, per the paper's funding statement
Topics
Health effects, Chemicals
Checked against
Abstract (Europe PMC, PMID 38213907, PMC10783259); funder via Crossref