Research library

Human study (observational)

Microplastics in the olfactory bulb of the human brain

Amato-Lourenço LF, Dantas KC, Júnior GR, et al. (2024). JAMA Network Open.

What they found

Micro-FTIR found 16 synthetic polymer particles and fibres in the olfactory bulbs (the brain's smell centre, just above the nose) of 8 of 15 deceased adults. Polypropylene was most common (43.8%); particles measured 5.5–26.4 µm. The authors suggest the nose could be a route into the brain.

Sample
15 autopsied adults in São Paulo
What it can't tell you
Case series of 15 people with very few particles in total. The µFTIR set-up resolved down to about 3 µm, so nanoplastics could not be detected. The route via the nose is a hypothesis, not shown. No health outcomes.
Funding
Alexander von Humboldt Foundation, Plastic Soup Foundation (an advocacy group), Brazilian CNPq and FAPESP; no conflicts reported
Topics
In the body
Checked against
Abstract and full text (PMC11406405): results, blanks ('absent in procedural blank and negative control filters'), funding

Where we cite it