Association of urinary bisphenol A concentration with medical disorders and laboratory abnormalities in adults
Lang IA, Galloway TS, Scarlett A, Henley WE, Depledge M, Wallace RB, Melzer D (2008). JAMA.
What they found
An early large human study of BPA and adult disease: higher urinary BPA was associated with cardiovascular diagnoses (odds ratio 1.39 per standard deviation) and diabetes (odds ratio 1.39), plus abnormal liver enzymes.
Read this too
JAMA ran an accompanying editorial (vom Saal and Myers, 2008) and three letters in 2009 commenting on the analysis (e.g., Young and Yu, doi 10.1001/jama.2009.122), with an author reply. We have not read them.
- Sample
- 1,455 US adults (NHANES 2003–2004)
- What it can't tell you
- Cross-sectional, with one urine sample: cannot tell whether BPA came before disease, and people with illness may eat or medicate differently. Self-reported diagnoses.
- Funding
- Not stated in the abstract
- Topics
- Health effects, Chemicals
- Checked against
- Abstract (Europe PMC, PMID 18799442); Crossref shows no corrections